Curcuma longa rhizome containing polyphenol curcuminoids (curcumin, demethoxycurcumin, bisdemethoxycurcumin). Curcumin is a master anti-inflammatory agent that inhibits NF-kB, COX-2, 5-LOX, and TNF-alpha, restoring joint mobility and reducing chronic systemic inflammation.
Educational information only — never stop or change a prescribed medication without talking to your prescriber first.
Poorly absorbed without black pepper or healthy fats. Caution in individuals with active bile duct obstruction or gallstones. High doses may enhance anticoagulant/antiplatelet medications.
Evidence level: Strong
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