Annona muricata fruit and leaves, containing annonaceous acetogenins (annonacin), isoquinoline alkaloids, and flavonoids. Soursop acts on 5-HT1A serotonin receptors to produce mild sedation and anxiety relief, promotes peripheral vasodilation to lower blood pressure, and suppresses inflammatory cytokines.
Educational information only — never stop or change a prescribed medication without talking to your prescriber first.
DO NOT CONSUME HIGH DOSES FOR PROLONGED PERIODS. Excessive long-term consumption of annonacin-rich soursop seeds and leaves has been linked to atypical Parkinsonian-like neurotoxicity. Avoid during pregnancy and Parkinson's disease. Safe when used moderately in cycles.
Evidence level: Moderate
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