HerbsRx
Strong evidence

Ashwagandha

Withania somnifera (Indian Ginseng), a premier Ayurvedic rasayana adaptogen. Rich in withanolides (withaferin A, withanolide A), ashwagandha modulates the hypothalamic-pituitary-adrenal (HPA) axis, reducing serum cortisol levels by up to 30%, while supporting thyroid hormone synthesis, muscle recovery, and cognitive resilience.

What Ashwagandha is used for

  • Chronic Stress
  • Anxiety
  • Cortisol Imbalance
  • Fatigue
  • Insomnia
  • Thyroid (Hypothyroid Support)
  • Muscle Strength
  • Athletic Endurance
  • Male Fertility

Pharmaceuticals Ashwagandha is studied as a natural alternative to

  • Xanax
  • Klonopin
  • Lexapro
  • Levothyroxine (mild supportive)
  • Sleep aids
  • Testosterone boosters

Educational information only — never stop or change a prescribed medication without talking to your prescriber first.

Safety and warnings

⚠️

May stimulate thyroid hormone production (monitor if taking levothyroxine/Synthroid). Avoid during pregnancy. Caution with autoimmune conditions or central nervous system depressants.

Evidence level: Strong

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