HerbsRx
Strong evidence

Licorice Root

The sweet root of Glycyrrhiza glabra. Contains glycyrrhizin, which inhibits the breakdown of cortisol (11-beta-HSD2) supporting adrenal recovery, and flavonoid glabridin. In deglycyrrhizinated (DGL) form, it stimulates mucosal secretion and cell proliferation, coating and healing stomach ulcers and esophagus tissues.

What Licorice Root is used for

  • Acid Reflux (GERD)
  • Gastritis
  • Stomach Ulcers
  • Sore Throat
  • Cough
  • Adrenal Fatigue
  • Chronic Fatigue

Pharmaceuticals Licorice Root is studied as a natural alternative to

  • Prilosec (Omeprazole)
  • Pepcid (Famotidine)
  • Pepto-Bismol
  • Mucinex
  • Cortisone (supportive)

Educational information only — never stop or change a prescribed medication without talking to your prescriber first.

Safety and warnings

⚠️

WHOLE (non-DGL) licorice can cause sodium retention, potassium loss, and elevated blood pressure if taken in high doses (>500 mg glycyrrhizin/day) for over 4 weeks. For acid reflux and long-term daily use, ALWAYS use Deglycyrrhizinated Licorice (DGL).

Evidence level: Strong

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