Comfrey (Symphytum officinale), or Knitbone, is one of the most powerful skin and bone healing agents known. Its roots and leaves contain exceptionally high levels of allantoin—a cell-proliferant compound that stimulates rapid cell division and accelerates tissue and bone regeneration. It also contains abundant mucilage and rosmarinic acid, which quickly reduce inflammation, swelling, and localized pain in sprains and closed fractures.
Educational information only — never stop or change a prescribed medication without talking to your prescriber first.
CRITICAL: Comfrey contains hepatotoxic pyrrolizidine alkaloids (PAs) that can cause liver failure if ingested internally. Never consume comfrey orally. Never apply comfrey to open, bleeding, or broken skin, as PAs can enter the bloodstream. Use only PA-free topical preparations.
Evidence level: Strong
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