Allium sativum bulb containing alliin, converted by alliinase into allicin upon crushing, and S-allyl cysteine (SAC) in aged extracts. Garlic stimulates nitric oxide and hydrogen sulfide (H2S) signaling, producing robust arterial vasodilation, lowering systolic blood pressure, inhibiting HMG-CoA reductase to reduce LDL cholesterol, and preventing platelet aggregation.
Educational information only — never stop or change a prescribed medication without talking to your prescriber first.
Possesses antiplatelet and mild anticoagulant effects; exercise caution with prescription blood thinners. Discontinue high-dose supplements 7-10 days before surgery. May cause gastrointestinal upset or body odor.
Evidence level: Strong
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