Silybum marianum seeds, containing the silymarin flavonolignan complex (chiefly silibinin A & B). Silibinin stabilizes hepatocyte cell membranes preventing toxin uptake, stimulates nucleolar RNA polymerase I to accelerate liver protein synthesis and regeneration, and preserves intracellular glutathione pools.
Educational information only — never stop or change a prescribed medication without talking to your prescriber first.
Extremely well tolerated. May produce a mild laxative effect due to increased bile flow. Caution in individuals with Asteraceae family allergies.
Evidence level: Strong
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